99% Isotretinoin CAS 4759-48-2 with Best Price CAS NO.4759-48-2

Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect.

Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other areas in the world. We have established close and stable cooperative relationships with over 200 domestic pharmaceutical and chemical enterprises. With high quality and favorable price, we′ re pleased to get your inquiry and we will reply you as soon as possible.

We will continue to forge ahead and strive hard for excellence, keep on exploring and progressing to develop more high-tech products with superior quality, to satisfy increasing demand of the clients, and create more value for our partners!

Product Name: Isotretinoin
Synonyms: Tretinoin EP Impurity A;Tretinoin Impurity 1retinoin EP Impurity ARETINOIC ACID, 13-CIS-;3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-cis-4-trans-6-trans-8-trans-nonatetraenoic acid;3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2Z,4E,6E,8E-NONATETRANENOIC ACID;13-CIS-RETINOIC ACID;13-cis-vitamin a acid;(L)-ISOTRETINOIN
CAS: 4759-48-2
MF: C20H28O2
MW: 300.44
EINECS: 225-296-0
Melting point: 172-175℃(lit.)
Boiling point: 381.66℃ (rough estimate)
Density: 1.0597 (rough estimate)
Chemical Properties: Yellow-Orange Crystalline Powder
Solubility: Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.

Description:

This product is rapidly absorbed after oral administration. The plasma concentration reaches peak within 2 to 4 hours. However, oral administration has a low bioavailability which can be boosted by postprandial medication. It has a over 99% binding rate to the plasma protein. It is mainly metabolized in the liver or intestine wall. It enters into the enterohepatic circulation in the form of prototype and metabolites. Prototype drug without any changes is excreted from the feces while metabolite is excreted from the urine. The half life of elimination lasts 10 to 20 hours.

Uses:

Used as a treatment for severe acne. Presently being studied in conjuction with the treatment of photoaged skin.

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Hubei Yuanmeng Biological Technology Co., Ltd.
Room 3820, Building 2, Vanke Golden City, Hongshan District, Wuhan, Hubei, China
Fiona Wei / Sales Manager