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    Tel: 86-027-68897569

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Home > Products >  Good Quality Idelalisib CAS 870281-82-6

Good Quality Idelalisib CAS 870281-82-6 CAS NO.870281-82-6

  • FOB Price: USD: 3.00-5.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: T/T,Other
  • Available Specifications:

    99%(1-5)Kilogram99%(5-25)Kilogram

  • Product Details

Keywords

  • Idelalisib
  • Idelalisib powder
  • Idelalisib supplier

Quick Details

  • ProName: Good Quality Idelalisib CAS 870281-82-...
  • CasNo: 870281-82-6
  • Molecular Formula: C22H18FN7O
  • Appearance: white powder
  • Application: Medical use
  • DeliveryTime: The parcel can be arranged within 24 h...
  • PackAge: foil bag or as your requirement
  • Port: Wuhan
  • ProductionCapacity: 1000 Kilogram/Month
  • Purity: 99%
  • Storage: 2-8°C
  • Transportation: By Express, by air, by sea
  • LimitNum: 1 Kilogram
  • Related Substances: 0.021%
  • Residue on Ignition: <0.1%
  • Heavy Metal: < 10 ppm
  • Valid Period: 2 years

Superiority

Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect.

Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other areas in the world. We have established close and stable cooperative relationships with over 200 domestic pharmaceutical and chemical enterprises. With high quality and favorable price, we′ re pleased to get your inquiry and we will reply you as soon as possible.

We will continue to forge ahead and strive hard for excellence, keep on exploring and progressing to develop more high-tech products with superior quality, to satisfy increasing demand of the clients, and create more value for our partners!

Details

Idelalisib

Product Name: CAL-101, Idelalisib
CAS: 870281-82-6
MF: C22H18FN7O
MW: 415.42
EINECS: 807-438-9

Melting point: 250-252°C
Boiling point: 733.4±70.0 °C(Predicted)
Density: 1.47
Storage temp.: -20°C

Description:

Idelalisib (CAS 870281-82-6) is a potent (IC50 = 2.5nM) and selective (IC50’s: PI3Ka = 820nM, PI3Kb = 565nM, PI3Kg = 89nM) PI3Kd inhibitor.1,2 Useful clinical agent for the treatment of various blood cancers. Idelalisib attenuates regulatory T cells (Treg) but not conventional T cells (Tconv) resulting in a significant increase in tumor-infiltrating antigen-specific CD8 T cells in a murine lung cancer model.3 Conversely, systemic PI3Kd inactivation antagonized anti-CTLA-4 and anti-PD-L1 treatment.4 Others have found that Idelalisib minimally influenced rituximab- and obinutuzumab-mediated Ab-dependent cellular cytotoxicity in human lymphoma cells.5

Uses:

CAL-101 is a PI3K/mTOR pathway inhibitor used in the treatment of myeloid leukemia through sensitizing the cells to combatting drugs. Potent PI3K-p110-delta inhibitor.
 

 

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Make an order Please make clear what product and what quantity you need
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Packing Select best ways according to quantity and safety degree(Super discreet, professional and experienced)
Lead time Within 24 hours upon receipt of payment
Package picture Photos of package would be offered to tell apart the items
Tracking number Offered once it is released
Shipping time around 15 days after receiving the payment
After-sale service 24/7 Online for any problems



Contact us!

Hubei Yuanmeng Biological Technology Co., Ltd.
Room 3820, Building 2, Vanke Golden City, Hongshan District, Wuhan, Hubei, China
Fiona Wei / Sales Manager

 

 

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